Karen S Wilcox Selected Research

Drug Therapy (Chemotherapy)

1/2020	Ultrastructural and functional changes at the tripartite synapse during epileptogenesis in a model of temporal lobe epilepsy.
7/2017	Evaluation of Cannabidiol in Animal Seizure Models by the Epilepsy Therapy Screening Program (ETSP).
3/2017	Hippocampal TNFα Signaling Contributes to Seizure Generation in an Infection-Induced Mouse Model of Limbic Epilepsy.
12/2016	Acute treatment with minocycline, but not valproic acid, improves long-term behavioral outcomes in the Theiler's virus model of temporal lobe epilepsy.

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Karen S Wilcox Research Topics

Disease

35	Seizures (Absence Seizure) 03/2024 - 02/2002
27	Epilepsy (Aura) 01/2022 - 02/2002
10	Infections 03/2024 - 07/2010
8	Temporal Lobe Epilepsy 01/2022 - 05/2007
7	Drug Resistant Epilepsy 10/2023 - 12/2006
7	Status Epilepticus (Complex Partial Status Epilepticus) 01/2022 - 01/2012
4	Virus Diseases (Viral Diseases) 09/2019 - 03/2010
3	Gliosis 01/2019 - 03/2010
3	Inflammation (Inflammations) 03/2017 - 06/2008
2	Central Nervous System Infections (Central Nervous System Infection) 09/2019 - 03/2017
2	Pain (Aches) 07/2017 - 09/2006
2	Cognitive Dysfunction 04/2014 - 03/2012
2	Benign Neonatal Epilepsy (Benign Familial Neonatal Convulsions) 07/2009 - 07/2008
1	Neoplasms (Cancer) 01/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2021
1	Stroke (Strokes) 01/2021
1	Brain Injuries (Brain Injury) 01/2019
1	Memory Disorders (Memory Loss) 09/2017
1	Neuralgia (Stump Neuralgia) 07/2017
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2016
1	Picornaviridae Infections 01/2016
1	Disease Progression 04/2014
1	Sclerosis 04/2014
1	Generalized Epilepsy 11/2013
1	AIDS-Related Complex (ARC) 03/2012

Drug/Important Bio-Agent (IBA)

10	Anticonvulsants (Antiepileptic Drugs)IBA 01/2020 - 02/2002
7	Kainic Acid (Kainate)IBA 01/2022 - 05/2007
4	Valproic Acid (Depakote)FDA LinkGeneric 01/2022 - 02/2002
4	Lamotrigine (Lamictal)FDA LinkGeneric 09/2019 - 09/2006
4	Glutamic Acid (Glutamate)FDA Link 01/2019 - 08/2011
4	Pentylenetetrazole (Metrazol)IBA 07/2017 - 02/2002
3	CytokinesIBA 03/2024 - 07/2011
3	Messenger RNA (mRNA)IBA 03/2017 - 03/2010
3	Minocycline (Cyclops)FDA LinkGeneric 12/2016 - 07/2011
3	Potassium Channels (Potassium Channel)IBA 07/2013 - 07/2008
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 03/2012 - 11/2008
3	Interleukin-6 (Interleukin 6)IBA 10/2011 - 03/2010
2	Phenobarbital (Luminal)FDA Link 01/2022 - 09/2019
2	ezogabine (retigabine)IBA 01/2022 - 07/2013
2	Tiagabine (Gabitril)FDA Link 01/2022 - 09/2019
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 04/2014
2	CannabidiolIBA 09/2019 - 07/2017
2	Proteins (Proteins, Gene)FDA Link 09/2019 - 03/2017
2	gamma-Aminobutyric Acid (GABA)IBA 09/2019 - 12/2006
2	Antidepressive Agents (Antidepressants)IBA 07/2017 - 06/2008
2	Formaldehyde (Formol)FDA Link 07/2017 - 09/2006
2	Glutamate Receptors (Glutamate Receptor)IBA 03/2017 - 01/2016
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2017 - 03/2010
2	N-Methylaspartate (NMDA)IBA 01/2016 - 03/2012
2	Carbamazepine (Tegretol)FDA LinkGeneric 05/2015 - 07/2013
2	BicucullineIBA 01/2012 - 02/2002
2	GABA-A Receptors (GABA(A) Receptor)IBA 12/2006 - 06/2006
1	CalciumIBA 03/2024
1	Purinergic Receptors (Receptors, Purine)IBA 03/2024
1	BenzodiazepinesIBA 01/2022
1	Gabapentin (Neurontin)FDA LinkGeneric 01/2022
1	Topiramate (Topamax)FDA LinkGeneric 01/2022
1	Levetiracetam (Keppra)FDA LinkGeneric 01/2022
1	Lacosamide FDA Link 01/2022
1	Midazolam (Versed)FDA LinkGeneric 01/2022
1	Phenytoin (Dilantin)FDA LinkGeneric 01/2022
1	Vitamin K FDA Link 11/2020
1	Clobazam (HR 376)IBA 09/2019
1	Sodium Channel BlockersIBA 09/2019
1	Clonazepam (Rivotril)FDA LinkGeneric 09/2019
1	GABA Receptors (GABA Receptor)IBA 09/2019
1	Metabotropic Glutamate 5 ReceptorIBA 01/2019
1	Amino Acid Transport System X-AG (Glutamate Transporter)IBA 01/2019
1	Excitatory Amino Acid AntagonistsIBA 11/2018
1	Analgesics (Analgesic Drugs)IBA 07/2017
1	Acetaminophen (Paracetamol)FDA LinkGeneric 07/2017
1	Type II Tumor Necrosis Factor ReceptorsIBA 03/2017
1	Type I Tumor Necrosis Factor ReceptorsIBA 03/2017
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 03/2017
1	GYKI 52466IBA 01/2016
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2016
1	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 01/2016
1	Ionotropic Glutamate ReceptorsIBA 01/2016
1	Dizocilpine Maleate (Dizocilpine)IBA 01/2016
1	2,3- dioxo- 6- nitro- 7- sulfamoylbenzo(f)quinoxaline (NBQX)IBA 01/2016
1	salicylhydroxamic acid (SHAM)IBA 04/2014
1	cresyl violetIBA 04/2014
1	Kainic Acid Receptors (Kainate Receptor)IBA 10/2013
1	Antisense OligonucleotidesIBA 03/2012
1	Dopamine (Intropin)FDA LinkGeneric 03/2012
1	AcidsIBA 03/2012
1	Methamphetamine (Desoxyn)FDA LinkGeneric 03/2012
1	OrganophosphatesIBA 01/2012
1	SomanIBA 01/2012

Therapy/Procedure

22	Therapeutics 01/2022 - 09/2006
4	Drug Therapy (Chemotherapy) 01/2020 - 12/2016
1	Lasers (Laser) 03/2024
1	Deep Brain Stimulation 10/2023
1	Ultrasonic Therapy 01/2023
1	Induced Hyperthermia (Thermotherapy) 01/2021
1	Intraperitoneal Injections 01/2021
1	Secondary Prevention 01/2021
1	Investigational Therapies (Experimental Therapy) 07/2017
1	Ligation 07/2017